Description
Domperidone is a medication that belongs to the class of drugs called dopamine antagonists. It is used to treat symptoms of nausea, vomiting, and stomach bloating caused by certain medical conditions or medications. It works by blocking the action of dopamine, a chemical messenger in the brain that is responsible for the feeling of nausea and vomiting.
Direction of Use:
Domperidone is typically taken orally, usually 3-4 times a day, before meals and at bedtime.
Contraindications:
Domperidone is contraindicated in patients with known hypersensitivity to domperidone and in patients with moderate or severe liver dysfunction.
Doses and Administration:
The usual adult dose is 10-20 mg, 3-4 times daily, before meals and at bedtime. The dose may be adjusted based on the patient’s response to the treatment.
Side Effects:
Common side effects include headache, diarrhea, and constipation. More serious side effects include heart rhythm problems, drowsiness, and abnormal movements of the face or tongue.
Interactions:
Domperidone may interact with other medications, such as anti-depressants and anti-psychotics. It also may interact with alcohol, increasing the risk of side effects.
Warnings and Precautions:
Domperidone should be used with caution in patients with a history of heart problems or liver disease. It is important to inform your healthcare provider if you have any medical conditions or are taking any other medications before starting treatment with domperidone. Patients should be advised to avoid alcohol while on treatment. If you experience severe or prolonged side effects or if your condition worsens, stop using the medication and contact your healthcare provider.






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